As a research technician I am supporting the project “Antiviral defence in the vector mosquito Aedes aegypti, induction and suppression of RNA silencing pathways”.
Hogeschool van Arnhem en Nijmegen, Nijmegen, The Netherlands. Chemical Laboratory Science – Graduation option Biochemistry. 1996 – 2000.
Research Technician. Radboudumc, Nijmegen, The Netherlands. Department of Orthodontics and Craniofacial Biology (Prof. AM Kuijpers-Jagtman). 2011 – 2014.
At the department of Orthodontics and Craniofacial Biology I supported the project “Induction of cyto protective proteins as a new strategy against hypertrophic scar formation by oxidative stress and inflammation”.
Research Technician. University Medical Center St Radboud, Nijmegen, The Netherlands. Department of Pharmacology and Toxicology (Prof. Smits and Prof. Russel). 2005 – 2010.
At the department of Pharmacology and Toxicology I was part of a team researching fundamental heme oxygenase biology focusing on the reduction of wound contraction.
Project title: “Targeting the heme heme oxygenase system: a novel therapeutic approach for the reduction of wound contraction”.
Reseach Technician. Radboud University Nijmegen, The Netherlands. Department of Molecular Biology (Prof. Henk Stunnenberg). 2000 – 2004.
At the department of Molecular Biology (investigating the fundamental mechanisms of transcriptional regulation and chromosome structures) I supported a research team that looked into the underlying mechanisms of leukemia with the focus on transcriptional regulation of gene expression by hormone receptors. Much of the work done involved elucidating the histone code surrounding promoter regions using the ChIP technique coupled to quantitative real time PCR.
Internship. Radboud University Nijmegen, The Netherlands. Department of Biochemistry (Dr. Toin van Kuppevelt). 1999 – 2000.
At the department of Biochemistry I performed my traineeship and looked into possible uses of scFv antibody fragments in heparan sulfate research and made the first steps in finding out what (heparan sulfate) structure a specific single chain antibody recognizes in the Wilms’ tumor cell line.